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MIT AI reveals how antibiotic targets Crohn’s bacteria

MIT and McMaster researchers used AI to map how a narrow-spectrum antibiotic attacks harmful gut bacteria. Enterololin targets E. coli linked to Crohn’s flares while preserving most of the microbiome, providing a precise alternative to broad-spectrum antibiotics.

AI accelerated the process of identifying the drug’s mechanism of action, reducing a task that usually takes years to just months.

The team used DiffDock, a generative AI tool developed at MIT, to predict how enterololin binds to a protein complex called LolCDE in E. coli. Laboratory experiments, including mutant evolution, RNA sequencing, and CRISPR knockdowns, confirmed the AI predictions.

The method demonstrates how AI can provide mechanistic insights, guide experiments, and speed up early-stage antibiotic development.

Enterololin improved recovery and preserved the microbiome in mouse models compared with conventional treatments. Researchers aim to develop derivatives against resistant pathogens like Klebsiella pneumoniae, with early work underway at spinout company Stoked Bio.

The study highlights broader implications for precision antibiotics, which could treat infections without disrupting beneficial microbes. AI-driven mechanism mapping could speed up drug discovery, cut costs, and help tackle antimicrobial resistance.

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New AI tools make Facebook Reels more engaging than ever

Facebook enhances how users find and share Reels, focusing on personalisation and social interaction.

The platform’s new recommendation engine learns user interests faster, presenting more relevant and up-to-date content. Video viewing time in the US has risen over 20% year-on-year, reflecting the growing appeal of both short and long-form clips.

The update introduces new ‘friend bubbles’ showing which Reels or posts friends have liked, allowing users to start private chats instantly.

A feature that encourages more spontaneous conversation and discovery through shared interests. Facebook’s ‘Save’ option has also been simplified, letting users collect favourite posts and Reels in one place, while improving future recommendations.

AI now plays a larger role in content exploration, offering suggested searches on certain Reels to help users find related topics without leaving the player. By combining smarter algorithms with stronger social cues, Facebook aims to make video discovery more meaningful and community-driven.

Further personalisation tools are expected to follow as the platform continues refining its Reels experience.

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Study explores AI’s role in future-proofing buildings

AI could help design buildings that are resilient to both climate extremes and infectious disease threats, according to new research. The study, conducted in collaboration with Charles Darwin University, examines the application of AI in smart buildings, with a focus on energy efficiency and management.

Buildings account for over two-thirds of global carbon emissions and energy consumption, but reducing consumption remains challenging and costly. The study highlights how AI can enhance ventilation and thermal comfort, overcoming the limitations of static HVAC systems that impact sustainability and health.

Researchers propose adaptive thermal control systems that respond in real-time to occupancy, outdoor conditions, and internal heat. Machine learning can optimise temperature and airflow to balance comfort, energy efficiency, and infection control.

A new framework enables designers and facility managers to simulate thermal scenarios and assess their impact on the risk of airborne transmission. It is modular and adaptable to different building types, offering a quantitative basis for future regulatory standards.

The study was conducted with lead author Mohammadreza Haghighat from the University of Tehran and CDU’s Ehsan Mohammadi Savadkoohi. Future work will integrate real-time sensor data to strengthen building resilience against future climate and health threats.

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Spotify links with ChatGPT to enhance personalised listening experiences

Spotify and OpenAI have combined music and podcast discovery into ChatGPT conversations. Free and Premium users can now link their Spotify accounts to ChatGPT and receive personalised recommendations directly within chat.

Once connected, users can prompt ChatGPT with queries like ‘play something mellow for reading’ or ‘recommend a science podcast’, and Spotify will surface results inline. Tapping a track or episode directs the user to the Spotify app for playback.

Spotify emphasises that this feature is optional and user consent is required. No audio or video content from Spotify will be shared with OpenAI for model training purposes.

Free users will still draw from Spotify’s existing playlists (such as Discover Weekly or New Music Friday). In contrast, Premium users will gain access to more refined, bespoke suggestions based on richer prompts.

The integration is available in English across 145 countries and works on desktop and mobile for ChatGPT Free, Plus and Pro users.

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Could AI win a Nobel Prize? Experts debate the possibility

AI is starting to make inroads into scientific discovery. In recent years, AI systems have analysed data, designed experiments, and even proposed hypotheses and behaviours once thought to be uniquely human.

Some researchers now argue that AI could compete with leading scientists, conceivably worthy of a Nobel Prize in a few decades. The ambition invites provocative questions: Can a machine be an author or laureate? What criteria would apply? Would human oversight remain essential?

Sceptics argue that AI lacks consciousness, intentionality or moral agency, all hallmarks of great scientific insight. They caution that the machine’s contributions are derivative, built on human data, models and frameworks. Others contend that denying AI recognition blocks a future where hybrid human-machine teams deliver breakthroughs.

Meanwhile, mechanisms for attributing credit are also under scrutiny. Would the institution or the engineers who built the AI deserve the credit, or the AI itself? The article notes existing examples: AIs have already co-authored papers and databases in genetics or materials science. However, instituting them as Nobel candidates demands shifting philosophical and institutional norms.

As AI systems achieve deeper autonomy, the debate over their role in science and whether they merit high honours will only intensify. The Nobel Prize, a symbolic instrument in the science ecosystem, may evolve to include nonhuman actors if the community permits it.

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Sanders warns AI could erase 100 million US jobs

Senator Bernie Sanders has warned that AI and automation could eliminate nearly 100 million US jobs within the next decade unless stronger worker protections are introduced.

The report, titled The Big Tech Oligarchs’ War Against Workers, claims that companies such as Amazon, Walmart, JPMorgan Chase, and UnitedHealth already use AI to reduce their workforces while rewarding executives with multimillion-dollar pay packages.

According to the findings, nearly 90% of US fast-food workers, two-thirds of accountants, and almost half of truck drivers could see their jobs replaced by automation. Sanders argues that technological progress should enhance people’s lives rather than displace them,

His proposals include introducing a 32-hour workweek without loss of pay, a ‘robot tax’ for companies that replace human labour, and giving workers a share of profits and board representation.

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Anthropic launches Bengaluru office to drive responsible AI in India

AI firm Anthropic, the company behind the Claude AI chatbot, is opening its first office in India, choosing Bengaluru as its base.

A move that follows OpenAI’s recent expansion into New Delhi, underlining India’s growing importance as a hub for AI development and adoption.

CEO Dario Amodei said India’s combination of vast technical talent and the government’s commitment to equitable AI progress makes it an ideal location.

The Bengaluru office will focus on developing AI solutions tailored to India’s needs in education, healthcare, and agriculture sectors.

Amodei is visiting India to strengthen ties with enterprises, nonprofits, and startups and promote responsible AI use that is aligned with India’s digital growth strategy.

Anthropic plans further expansion in the Indo-Pacific region, following its Tokyo launch, later in the year.

Chief Commercial Officer Paul Smith noted the rising demand among Indian companies for trustworthy, scalable AI systems. Anthropic’s Claude models are already accessible in India through its API, Amazon Bedrock, and Google Cloud Vertex AI.

The company serves more than 300,000 businesses worldwide, with nearly 80 percent of usage outside the US.

India has become the second-largest market for Claude, with developers using it for tasks such as mobile UI design and web app debugging.

Anthropic also enhances Claude’s multilingual capabilities in major Indic languages, including Hindi, Bengali, and Tamil, to support education and public sector projects.

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OpenAI unveils AgentKit for faster AI agent creation

OpenAI has launched AgentKit, a new suite of developer tools designed to simplify AI-powered agents’ creation, deployment, and optimisation. The platform unifies workflows that previously required multiple systems, offering a faster and more visual way to build intelligent applications.

AgentKit’s AI includes Agent Builder, Connector Registry, ChatKit, and advanced evaluation tools. Developers can now design multi-agent workflows on a visual canvas, manage data connections across workspaces, and integrate chat-based agents directly into apps and websites.

Early users such as Ramp and LY Corporation built working agents in just a few hours, cutting development cycles by up to 70%. Companies including Canva and HubSpot have used ChatKit to embed conversational support agents, transforming customer experience and developer engagement.

New evaluation features and reinforcement fine-tuning allow users to test, grade, and improve agents’ reasoning abilities. AgentKit is now available to developers and enterprises through OpenAI’s API and ChatGPT Enterprise, with a wider rollout expected later this year.

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Bulgaria eyes AI gigafactory partnership with IBM

Bulgaria is considering building an AI gigafactory in partnership with IBM and the European Commission, Prime Minister Rosen Zhelyazkov announced after meeting with IBM executives in Sofia. The project aims to attract large-scale high-tech investment and strengthen Europe’s AI infrastructure.

The proposed facility would feature over 100,000 advanced GPU chips and require up to 500 megawatts of power. The initial phase alone is expected to need around 70 megawatts, highlighting the scale of the planned operation.

Funding could come through a public-private partnership, with the European Commission covering up to 17 percent of capital costs and EU member states contributing additional support for this Bulgarian project.

IBM is considered a strategic technology partner, bringing expertise in cloud computing, cybersecurity, and AI systems. The first gigafactories across Europe are expected to begin operations between 2027 and 2028, aligning with the EU’s plan to mobilise €200 billion for AI development.

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New report finds IT leaders unprepared for evolving cyber threats

A new global survey by 11:11 Systems highlights growing concerns among IT leaders over cyber incident recovery. More than 800 senior IT professionals across North America, Europe, and the Asia Pacific report a rising strain from evolving threats, staffing gaps, and limited clean-room infrastructure.

Over 80% of respondents experienced at least one major cyberattack in the past year, with more than half facing multiple incidents. Nearly half see recovery planning complexity as their top challenge, while over 80% say their organisations are overconfident in their recovery capabilities.

The survey also reveals that 74% believe integrating AI could increase cyberattack vulnerability. Despite this, 96% plan to invest in cyber incident recovery within the next 12 months, underlining its growing importance in budget strategies.

The financial stakes are high. Over 80% of respondents reported spending at least six figures during just one hour of downtime, with the top 5% incurring losses of over one million dollars per hour. Yet 30% of businesses do not test their recovery plans annually, despite these risks.

11:11 Systems’ CTO Justin Giardina said organisations must adopt a proactive, AI-driven approach to recovery. He emphasised the importance of advanced platforms, secure clean rooms, and tailored expertise to enhance cyber resilience and expedite recovery after incidents.

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