Digital standards

Estimating biological age from routine records with LifeClock

LifeClock, reported in Nature Medicine, estimates biological age from routine health records. Trained on 24.6 million visits and 184 indicators, it offers a low-cost route to precision health beyond simple chronology.

Researchers found two distinct clocks: a paediatric development clock and an adult ageing clock. Specialised models improved accuracy, reflecting scripted growth versus decline. Biomarkers diverged between stages, aligning with growth or deterioration.

LifeClock stratified risk years ahead. In children, clusters flagged malnutrition, developmental disorders, and endocrine issues, including markedly higher odds of pituitary hyperfunction and obesity. Adult clusters signalled future diabetes, stroke, renal failure, and cardiovascular disease.

Performance was strong after fine-tuning: the area under the curve hit 0.98 for current diabetes and 0.91 for future diabetes. EHRFormer outperformed RNN and gradient-boosting baselines across longitudinal records.

Authors propose LifeClock for accessible monitoring, personalised interventions, and prevention. Adding wearables and real-time biometrics could refine responsiveness, enabling earlier action on emerging risks and supporting equitable precision medicine at the population scale.

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Rare but real, mental health risks at ChatGPT scale

OpenAI says a small share of ChatGPT users show possible signs of mental health emergencies each week, including mania, psychosis, or suicidal thoughts. The company estimates 0.07 percent and says safety prompts are triggered. Critics argue that small percentages scale at ChatGPT’s size.

A further 0.15 percent of weekly users discuss explicit indicators of potential suicidal planning or intent. Updates aim to respond more safely and empathetically, and to flag indirect self-harm signals. Sensitive chats can be routed to safer models in a new window.

More than 170 clinicians across 60 countries advise OpenAI on risk cues and responses. Guidance focuses on encouraging users to seek real-world support. Researchers warn vulnerable people may struggle to act on on-screen warnings.

External specialists see both value and limits. AI may widen access when services are stretched, yet automated advice can mislead. Risks include reinforcing delusions and misplaced trust in authoritative-sounding output.

Legal and public scrutiny is rising after high-profile cases linked to chatbot interactions. Families and campaigners want more transparent accountability and stronger guardrails. Regulators continue to debate transparency, escalation pathways, and duty of care.

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New AI boards help Pinterest users refine taste and shop

Pinterest is giving boards an AI upgrade, adding smarter recommendations, fresher layouts, and built-in shopping to help users move from ideas to action worldwide over the coming months.

New tabs tailor each board: Make it yours for fashion and some home decor, More ideas for categories like beauty or recipes, and All saves as a single place to find everything previously pinned.

In the US and Canada, Styled for you creates dynamic AI collages from saved fashion Pins, letting people mix and match apparel and accessories, preview outfits, and shop items that fit their taste.

Pinterest is also testing Boards made for you, personalised boards curated with editorial input and AI picks, delivered to home feeds and inboxes, featuring trending styles, weekly outfit ideas, and shoppable looks.

Executives say boards remain central to Pinterest’s experience; the new AI features aim to act like a personal shopping assistant while keeping curation simple and privacy-respecting by design.

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Adobe Firefly expands with new AI tools for audio and video creation

Adobe has unveiled major updates to its Firefly creative AI studio, introducing advanced audio, video, and imaging tools at the Adobe MAX 2025 conference.

These new features include Generate Soundtrack for licensed music creation, Generate Speech for lifelike multilingual voiceovers, and a timeline-based video editor that integrates seamlessly with Firefly’s existing creative tools.

The company also launched the Firefly Image Model 5, which can produce photorealistic 4MP images with prompt-based editing. Firefly now includes partner models from Google, OpenAI, ElevenLabs, Topaz Labs, and others, bringing the industry’s top AI capabilities into one unified workspace.

Adobe also announced Firefly Custom Models, allowing users to train AI models to match their personal creative style.

In a preview of future developments, Adobe showcased Project Moonlight, a conversational AI assistant that connects across creative apps and social channels to help creators move from concept to content in minutes.

A system that can offer tailored suggestions and automate parts of the creative process while keeping creators in complete control.

Adobe emphasised that Firefly is designed to enhance human creativity rather than replace it, offering responsible AI tools that respect intellectual property rights.

With such a release, the company continues integrating generative AI across its ecosystem to simplify production and empower creators at every stage of their workflow.

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UK retail investors can now access crypto ETNs

The FCA has lifted the ban on retail access to certain crypto exchange trade notes (cETNs), effective 8 October. UK consumers can now invest in cETNs listed on the Official List and traded on a Recognised Investment Exchange.

Firms offering cETNs must meet strict requirements. Products are categorised as Restricted Mass Market Investments (RMMIs), meaning financial promotions cannot include incentives, and firms must carry out appropriateness assessments, client categorisation, and risk disclosures.

Compliance with the Consumer Duty is also required, including acting in good faith, avoiding foreseeable harm, and ensuring products meet the needs of the target market.

The FCA emphasises that cETNs are complex products, and firms should have the correct permissions to offer them. Those seeking authorisation or new permissions can request pre-application support meetings.

The regulator is also advancing its crypto roadmap to integrate crypto assets more fully into its regulatory framework, with ongoing consultations on applying Handbook rules to crypto activities.

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Yuan says AI ‘digital twins’ could trim meetings and the workweek

AI could shorten the workweek, says Zoom’s Eric Yuan. At TechCrunch Disrupt, he pitched AI ‘digital twins’ that attend meetings, negotiate drafts, and triage email, arguing assistants will shoulder routine tasks so humans focus on judgement.

Yuan has already used an AI avatar on an investor call to show how a stand-in can speak on your behalf. He said Zoom will keep investing heavily in assistants that understand context, prioritise messages, and draft responses.

Use cases extend beyond meetings. Yuan described counterparts sending their digital twins to hash out deal terms before principals join to resolve open issues, saving hours of live negotiation and accelerating consensus across teams and time zones.

Zoom plans to infuse AI across its suite, including whiteboards and collaborative docs, so work moves even when people are offline. Yuan said assistants will surface what matters, propose actions, and help execute routine workflows securely.

If adoption scales, Yuan sees schedules changing. He floated a five-year goal where many knowledge workers shift to three or four days a week, with AI increasing throughput, reducing meeting load, and improving focus time across organisations.

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IBM unveils Digital Asset Haven for secure institutional blockchain management

IBM has introduced Digital Asset Haven, a unified platform designed for banks, corporations, and governments to securely manage and scale their digital asset operations. The platform manages the full asset lifecycle from custody to settlement while maintaining compliance.

Built with Dfns, the platform combines IBM’s security framework with Dfns’ custody technology. The Dfns platform supports 15 million wallets for 250 clients, providing multi-party authorisation, policy governance, and access to over 40 blockchains.

IBM Digital Asset Haven includes tools for identity verification, crime prevention, yield generation, and developer-friendly APIs for extra services. Security features include Multi-Party Computation, HSM-based signing, and quantum-safe cryptography to ensure compliance and resilience.

According to IBM’s Tom McPherson, the platform gives clients ‘the opportunity to enter and expand into the digital asset space backed by IBM’s level of security and reliability.’ Dfns CEO Clarisse Hagège said the partnership builds infrastructure to scale digital assets from pilots to global use.

IBM plans to roll out Digital Asset Haven via SaaS and hybrid models in late 2025, with on-premises deployment expected in 2026.

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Citi and Coinbase unite to boost digital asset payments

Citi and Coinbase have announced a strategic partnership to enhance digital asset payment capabilities for institutional clients. The collaboration will begin by streamlining fiat transactions and strengthening links between traditional banking and digital assets via Coinbase’s on/off-ramps.

Both firms plan to introduce further initiatives in the coming months aimed at simplifying global access to crypto payments.

According to Citi’s Head of Payments, Debopama Sen, the partnership supports Citi’s goal of creating a ‘network of networks’ that enables borderless payments. Operating across 94 markets and 300 networks, Citi sees the move as progress towards integrating blockchain into mainstream finance.

Coinbase’s Brian Foster said the partnership merges Citi’s payments expertise with Coinbase’s digital asset leadership. Together, they aim to build next-generation infrastructure enabling seamless, round-the-clock access to crypto services for institutional clients.

The partnership builds on Citi’s ongoing investment in digital finance, including its Citi Token Services and 24/7 USD Clearing system. By aligning with Coinbase, the bank reinforces its commitment to innovation and positions itself at the forefront of the evolving digital money landscape.

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Elon Musk launches AI-powered Grokipedia to rival Wikipedia

Elon Musk has launched Grokipedia, an AI-driven online encyclopedia developed by his company xAI. The platform, described as an alternative to Wikipedia, debuted on Monday with over 885,000 articles written and verified by AI.

Musk claimed the early version already surpasses Wikipedia in quality and transparency, promising significant improvements with the release of version 1.0.

Unlike Wikipedia’s crowdsourced model, Grokipedia does not allow users to edit content directly. Instead, users can request modifications through xAI’s chatbot Grok, which decides whether to implement changes and explains its reasoning.

Musk said the project’s guiding principle is ‘the truth, the whole truth, and nothing but the truth,’ acknowledging the platform’s imperfections while pledging continuous refinement.

However, Grokipedia’s launch has raised questions about originality. Several entries contain disclaimers crediting Wikipedia under a Creative Commons licence, with some articles appearing nearly identical.

Musk confirmed awareness of the issue and stated that improvements are expected before the end of the year. The Wikimedia Foundation, which operates Wikipedia, responded calmly, noting that human-created knowledge remains at the heart of its mission.

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New ChatGPT model reduces unsafe replies by up to 80%

OpenAI has updated ChatGPT’s default model after working with more than 170 mental health clinicians to help the system better spot distress, de-escalate conversations and point users to real-world support.

The update routes sensitive exchanges to safer models, expands access to crisis hotlines and adds gentle prompts to take breaks, aiming to reduce harmful responses rather than simply offering more content.

Measured improvements are significant across three priority areas: severe mental health symptoms such as psychosis and mania, self-harm and suicide, and unhealthy emotional reliance on AI.

OpenAI reports that undesired responses fell between 65 and 80 percent in production traffic and that independent clinician reviews show significant gains compared with earlier models. At the same time, rare but high-risk scenarios remain a focus for further testing.

The company used a five-step process to shape the changes: define harms, measure them, validate approaches with experts, mitigate risks through post-training and product updates, and keep iterating.

Evaluations combine real-world traffic estimates with structured adversarial tests, so better ChatGPT safeguards are in place now, and further refinements are planned as understanding and measurement methods evolve.

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