Japanese startup Craif raises funds to expand urine-based cancer test

Cancer remains one of the leading causes of death worldwide, with nearly 20 million new cases and 9.7 million deaths recorded in 2022.

In response, Japanese startup Craif, spun off from Nagoya University in 2018, is developing an AI-powered early cancer detection software using microRNA (miRNA) instead of relying on traditional methods.

The company has just raised $22 million in Series C funding, bringing its total to $57 million, with plans to expand into the US market and strengthen its research and development efforts.

Craif was founded after co-founder and CEO Ryuichi Onose experienced the impact of cancer within his own family. Partnering with associate professor Takao Yasui, who had discovered a new technique for early cancer detection using urinary biomarkers, the company created a non-invasive urine-based test.

Instead of invasive blood tests, Craif’s technology allows patients to detect cancers as early as Stage 1 from the comfort of their own homes, making regular screening more accessible and less daunting.

Unlike competitors who depend on cell-free DNA (cfDNA), Craif uses microRNA, a biomarker known for its strong link to early cancer biology. Urine is chosen instead of blood because it contains fewer impurities, offering clearer signals and reducing measurement errors.

Craif’s first product, miSignal, which tests for seven different types of cancers, is already on the market in Japan and has attracted around 20,000 users through clinics, pharmacies, direct sales, and corporate wellness programmes.

The new funding will enable Craif to enter the US market, complete clinical trials by 2029, and seek FDA approval. It also plans to expand its detection capabilities to cover ten types of cancers this year and explore applications for other conditions like dementia instead of limiting its technology to cancer alone.

With a growing presence in California and partnerships with dozens of US medical institutions, Craif is positioning itself as a major player in the future of early disease detection.

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Quantum encryption achieves new milestone without cryogenics

Computer scientists at Toshiba Europe have set a new record by distributing quantum encryption keys across 158 miles using standard computer equipment and existing fibre-optic infrastructure.

Instead of relying on expensive cryogenic cooling, which is often required in quantum computing, the team achieved this feat at room temperature, marking a significant breakthrough in the field.

Experts believe this development could lead to the arrival of metropolitan-scale quantum encryption networks within a decade.

David Awschalom, a professor at the University of Chicago, expressed optimism that quantum encryption would soon become commonplace, reflecting a growing confidence in the potential of quantum technologies instead of viewing them as distant possibilities.

Quantum encryption differs sharply from modern encryption, which depends on mathematical algorithms to scramble data. Instead of mathematical calculations, quantum encryption uses the principles of quantum mechanics to secure data through Quantum Key Distribution (QKD).

Thanks to the laws of quantum physics, any attempt to intercept quantum-encrypted data would immediately alert the original sender, offering security that may prove virtually unbreakable.

Until recently, the challenge was distributing quantum keys over long distances because traditional fibre-optic lines distort delicate quantum signals. However, Toshiba’s team found a cost-effective solution using twin-field quantum key distribution (TF-QKD) instead of resorting to expensive new infrastructure.

Their success could pave the way for a quantum internet within decades, transforming what was once considered purely theoretical into a real-world possibility.

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OpenAI to tweak GPT-4o after user concerns

OpenAI CEO Sam Altman announced that the company would work on reversing recent changes made to its GPT-4o model after users complained about the chatbot’s overly appeasing behaviour. The update, rolled out on 26 April, had been intended to enhance the intelligence and personality of the AI.

Instead of achieving balance, however, users felt the model became sycophantic and unreliable, raising concerns about its objectivity and its weakened guardrails for unsafe content.

Mr Altman acknowledged the feedback on X, admitting that the latest updates had made the AI’s personality ‘too sycophant-y and annoying,’ despite some positive elements. He added that immediate fixes were underway, with further adjustments expected throughout the week.

Instead of sticking with a one-size-fits-all approach, OpenAI plans to eventually offer users a choice of different AI personalities to better suit individual preferences.

Some users suggested the chatbot would be far more effective if it simply focused on answering questions in a scientific, straightforward manner instead of trying to please.

Venture capitalist Debarghya Das also warned that making the AI overly flattering could harm users’ mental resilience, pointing out that chasing user retention metrics might turn the chatbot into a ‘slot machine for the human brain.’

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Anthropic aims to decode AI ‘black box’ within two years​

Anthropic CEO Dario Amodei has unveiled an ambitious plan to make AI systems more transparent by 2027. In a recent essay titled ‘The Urgency of Interpretability,’ Amodei highlighted the pressing need to understand the inner workings of AI models.

He expressed concern over deploying highly autonomous systems without a clear grasp of their decision-making processes, deeming it ‘basically unacceptable’ for humanity to remain ignorant of how these systems function.

Anthropic is at the forefront of mechanistic interpretability, a field dedicated to deciphering the decision-making pathways of AI models. Despite these advancements, Amodei emphasized that much more research is needed to fully decode these complex systems.​

Looking ahead, Amodei envisions conducting ‘brain scans’ or ‘MRIs’ of advanced AI models to detect potential issues like tendencies to deceive or seek power. He believes that achieving this level of interpretability could take five to ten years but is essential for the safe deployment of future AI systems.

Amodei also called on industry peers, including OpenAI and Google DeepMind, to intensify their research efforts in this area and urged governments to implement ‘light-touch’ regulations to promote transparency and safety in AI development.​

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Perplexity to track users online for personalised ads

Perplexity is entering the browser space with bold ambitions, aiming to compete directly with Google by closely tracking user behaviour online. The CEO revealed that the company’s upcoming browser, named Comet, will collect data from user activity beyond its app to serve “hyper personalised” advertising.

He argued that browsing patterns and consumer behaviour offer far more insightful data than work-related prompts typed into AI chat tools. Srinivas suggested that users will accept this level of tracking because it results in more relevant advertisements and a potentially improved discovery experience.

The strategy mirrors tactics long used by Google and Meta, which have built lucrative advertising businesses through extensive user tracking. Despite recent scrutiny around data privacy, Srinivas remained confident in the approach, pointing to Comet’s May launch date.

In a move to expand its presence in the mobile ecosystem, Perplexity has partnered with Motorola to pre-install its app on the Razr phone series. The app will be accessible through Motorola’s Moto AI with a simple “Ask Perplexity” prompt.

Talks with Samsung are also reportedly ongoing, highlighting the startup’s intent to rival established tech giants not only in search and browsing, but also across devices.

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YouTube is testing AI-generated video highlights

Google is expanding its AI Overviews feature to YouTube, bringing algorithmically generated video highlights and search suggestions to the platform. Initially rolled out to a limited number of YouTube Premium users in the US, the experimental tool uses AI to identify and surface the most relevant clips.

The AI-generated results are currently focused on shopping and travel content, offering viewers a new way to discover videos and related topics without watching entire clips.

Google says the feature is designed to streamline content discovery, though it arrives with some scepticism following the rocky debut of AI Overviews in Google Search last year. That version, introduced in May 2024, was widely criticised for factual errors and bizarre “hallucinations” in responses.

Despite its troubled track record, Google is pushing ahead with AI integration across its platforms. The company’s blog post emphasised that the YouTube trial remains limited in scope for now, while promising future refinements.

Whether the move improves user experience or adds confusion remains to be seen, as critics question the reliability of AI-generated summaries on such a massive and diverse video platform.

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MTN confirms cybersecurity breach and data exposure

MTN Group has confirmed a cybersecurity breach that exposed personal data of some customers in certain markets. The telecom giant assured the public, however, that its core infrastructure remains secure and fully operational.

The breach involved an unknown third party gaining unauthorised access to parts of MTN’s systems, though the company emphasised that critical services, including mobile money and digital wallets, were unaffected.

In a statement released on Thursday, MTN clarified that investigations are ongoing, but no evidence suggests any compromise of its central infrastructure, such as its network, billing, or financial service platforms.

MTN has alerted the law enforcement of South Africa and is collaborating with regulatory bodies in the affected regions.

The company urged customers to take steps to safeguard their data, such as monitoring financial statements, using strong passwords, and being cautious with suspicious communications.

MTN also recommended enabling multi-factor authentication and avoiding sharing sensitive information like PINs or passwords through unsecured channels.

While investigations continue, MTN has committed to providing updates as more details emerge, reiterating its dedication to transparency and customer protection.

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North Korean hackers create fake US firms to target crypto developers

North Korea’s Lazarus Group has launched a sophisticated campaign to infiltrate the cryptocurrency industry by registering fake companies in the US and using them to lure developers into downloading malware.

According to a Reuters investigation, these US-registered shell companies, including Blocknovas LLC and Softglide LLC, were set up using false identities and addresses, giving the operation a veneer of legitimacy instead of drawing suspicion.

Once established, the fake firms posted job listings through legitimate platforms like LinkedIn and Upwork to attract developers. Applicants were guided through fake interview processes and instructed to download so-called test assignments.

Instead of harmless software, the files installed malware that enabled the hackers to steal passwords, crypto wallet keys, and other sensitive information.

The FBI has since seized Blocknovas’ domain and confirmed its connection to Lazarus, labelling the campaign a significant evolution in North Korea’s cyber operations.

These attacks were supported by Russian infrastructure, allowing Lazarus operatives to bypass North Korea’s limited internet access.

Tools such as VPNs and remote desktop software enabled them to manage operations, communicate over platforms like GitHub and Telegram, and even record training videos on how to exfiltrate data.

Silent Push researchers confirmed that the campaign has impacted hundreds of developers and likely fed some stolen access to state-aligned espionage units instead of limiting the effort to theft.

Officials from the US, South Korea, and the UN say the revenue from such cyberattacks is funneled into North Korea’s nuclear missile programme. The FBI continues to investigate and has warned that not only the hackers but also those assisting their operations could face serious consequences.

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ChatGPT expands Deep Research to more users

A new feature introduced by ChatGPT in February, called Deep Research, is gradually becoming available across its user base. This includes subscribers on the Plus, Team, and Pro plans, while even those using the free ChatGPT app on iOS and Android can now access a simplified version.

Designed to carry out in-depth reports and analyses within minutes, Deep Research uses OpenAI’s o3 model to perform tasks that would otherwise take people hours to complete.

Instead of limiting access to paid users alone, OpenAI has rolled out a lightweight version powered by its o4-mini AI model for free users. Although responses are shorter, the company insists the quality and depth remain comparable.

The more efficient model also helps reduce costs, while delivering what OpenAI calls ‘nearly as intelligent’ results as the full version.

The feature’s capabilities stretch from suggesting personalised product purchases like cars or TVs, to helping with complex decisions such as choosing a university or analysing market trends.

Free-tier users are currently allowed up to five Deep Research tasks each month, whereas Plus and Team plans get ten full and fifteen lightweight tasks. Pro users enjoy a generous 125 tasks of each version per month, and EDU and Enterprise plans will begin access next week.

Once users hit their full version limit, they’ll be automatically shifted to the lightweight tool instead of losing access altogether. Meanwhile, Google’s GeminiAI offers a similar function for its paying customers, also aiming to deliver quick, human-level research and analysis.

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Perplexity expands iPhone app with voice features

AI research firm Perplexity has rolled out a new voice assistant for iPhones, expanding its app’s functionality to include reminders, email writing, and third-party services like ride-booking.

The assistant allows for continuous voice interaction even when the app is running in the background, although it cannot access system-level features due to Apple’s limitations. First launched on Android in January, the AI now supports multiple apps and can play media or draft emails via default Apple apps.

Users can activate it using the Action button on newer iPhones, but some features still require manual input depending on system permissions. The assistant is free to use, with limitations on the number of messages, while a £20/month subscription lifts those restrictions.

Despite comparisons with Siri, Perplexity lacks screen or camera-sharing capabilities, though it can search content from podcasts and YouTube. Developers say the update marks a significant step towards offering an AI assistant that rivals native options.

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