Stanford’s new AI model boosts liver transplant efficiency

Researchers aim to refine the model further and extend its use to heart and lung transplants, saving more lives.

Stanford Medicine has developed a machine learning model that predicts donor death timing, reducing cancelled liver transplants by 60% and improving efficiency.

A new machine learning model has been developed by Stanford Medicine researchers to make liver transplants more efficient. It predicts whether a donor will die within the time frame necessary for organ viability.

Donation after circulatory death requires that the donor pass within 30 to 45 minutes after life support removal; otherwise, surgeons often reject the liver due to increased risks for recipients. The model reduced futile procurements by 60%, outperforming surgeons’ predictions.

The algorithm analyses a wide range of donor data, including vital signs, blood work, neurological reflexes, and ventilator settings. The model was trained on over 2,000 cases from six US transplant centres and can be customised for hospital procedures and surgeon preferences.

The model also features a natural language interface that extracts relevant medical record information, streamlining the transplant workflow.

Donation after circulatory death is becoming increasingly important as it helps narrow the gap between organ demand and availability. Normothermic machine perfusion devices preserve organs during transport, making such donations more feasible.

Researchers hope the model will also be adapted for heart and lung transplants, further expanding its potential to save lives.

Stanford researchers stress that better predictions could help more patients receive life-saving transplants. Ongoing refinements aim to decrease missed opportunities from just over 15% to around 10%, enhancing efficiency and patient outcomes in organ transplantation.

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