Santander and Mastercard complete Europe’s first AI agent payment

Europe’s first end-to-end AI agent payment marks a new chapter in autonomous commerce and financial technology innovation.

Santander and Mastercard have executed Europe’s first live AI agent payment, signalling a major step forward for agentic commerce and automated financial transactions.

Spanish banking giant Banco Santander and Mastercard have completed what they describe as Europe’s first live end-to-end payment executed by an AI agent. The pilot combined Santander’s live payments infrastructure with Mastercard Agent Pay to enable autonomous, permission-based transactions.

Mastercard Agent Pay, launched in April 2025, allows AI agents to initiate and complete payments within predefined consumer limits. The transaction was orchestrated with support from PayOS and integrates Microsoft Azure OpenAI Service and Copilot Studio.

Following the pilot, Santander plans to expand testing and explore new partnerships across agentic commerce use cases. The bank, which manages around €1.84 trillion in assets, is positioning AI as a core driver of innovation.

AI initiatives at Santander are led by chief data and AI officer Ricardo Martín Manjón, hired from BBVA. A strategic partnership with OpenAI has also connected up to 30,000 employees to ChatGPT Enterprise in one of the fastest deployments of its kind.

Global competition in agentic payments is intensifying as Citi, US Bank and Westpac trial Mastercard Agent Pay. Westpac recently completed New Zealand’s first authenticated agentic transaction, while DBS, Visa, Axis Bank and RBL Bank are advancing similar intelligent commerce pilots.

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