AI analysis charts shifts in ageing research trends
A century of ageing science has been mapped using natural language processing and machine learning.
A new research paper published in Aging-US uses AI to map a century of global ageing research. The study analyses how scientific priorities have shifted over time. Underexplored areas are also identified.
Researchers analysed more than 460,000 scientific abstracts published between 1925 and 2023. Natural language processing and machine learning were used to cluster themes and track trends. The aim was to provide an unbiased view of the field’s evolution.
Findings show a shift from basic biological studies toward clinical research, particularly age-related diseases such as Alzheimer’s and dementia. Basic science continues to focus on cellular mechanisms. Limited overlap persists between laboratory and clinical research.
Several fast-growing topics, including autophagy, RNA biology, and nutrient sensing, remain weakly connected to clinical applications. Strong links endure in areas such as cancer and ageing. Other associations, including epigenetics and autophagy, are rarely explored.
The analysis highlights gaps that may shape future ageing research priorities. AI-based mapping provides insights into how funding and policy shape focus areas. Greater integration could support more effective translation into clinical outcomes.
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